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SAMe and Antidepressants: What You Need to Know About Mood Effects and Interaction Risks 2 Dec 2025
  • By Paul Gray
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SAMe and Antidepressants: What You Need to Know About Mood Effects and Interaction Risks

SAMe may help with mild depression, but combining it with antidepressants can trigger serotonin syndrome-a dangerous, potentially life-threatening reaction. Learn the risks, symptoms, and safe use guidelines.

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